Venlafaxine, commonly used for depression and anxiety disorders, is likely a serotonin-norepinephrine reuptake inhibitor with potential CNS activity based on its structure.
Research to validate its biological targets integrates experimental, computational, and multiomics approaches like computational target prediction and high-throughput screening.
Machine learning enhances prediction of target druggability by integrating diverse protein features, addressing data imbalance, and predicting drug-target interactions for faster drug discovery.
ML models can predict side effects, prioritize targets for specific diseases, and improve the efficiency of drug development by scoring and ranking targets based on predicted therapeutic effects.