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Wearable Hydrogel Ultrasound Device Enables Long-Term Neuromodulation
- A team of researchers has introduced a bioadhesive hydrogel-coupled, miniaturized ultrasound transducer system for long-term neuromodulation, outlined in a publication in Nature Communications.
- This technology targets deep brain regions with non-invasive ultrasound-based neuromodulation, addressing limitations of traditional methods such as poor skin adhesion and bulky designs.
- The system integrates a biomimetic hydrogel interface for comfortable and flexible skin adhesion, promoting continuous, long-term therapy application.
- The ultrathin ultrasound transducer ensures efficient acoustic energy transmission for stimulating neurons beneath the skin.
- The bioadhesive hydrogel used is biocompatible, breathable, and maintains strong adhesion even during sweating or movement, allowing for uninterrupted therapy sessions.
- The device is designed to conform closely to the body's contours, minimizing detachment and ensuring optimal performance.
- Optimized for low power consumption, the system's electrical and acoustic design parameters enable continuous operation without frequent battery changes.
- Customizable neuromodulation protocols offer high spatial resolution for targeting specific neuronal populations, catering to diverse clinical indications.
- Thorough biocompatibility and safety evaluations in animal models demonstrate the system's compliance with regulatory thresholds, supporting future human trials.
- The interdisciplinary collaboration behind this technology bridges materials science, electrical engineering, neurobiology, and clinical medicine, presenting a holistic approach to neuromodulation.
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