CMD and ENTRYPOINT are instructions in a Dockerfile used to specify commands for container startup.CMD sets the default command that can be overridden during runtime, while ENTRYPOINT sets a fixed command.CMD works as a suggestion for container behavior, while ENTRYPOINT behaves as a strict fixed instruction.Both CMD and ENTRYPOINT can be used together to provide default parameters and a fixed main command.CMD is useful for flexibility, allowing easy command changes, while ENTRYPOINT ensures consistency in command execution.Combining CMD and ENTRYPOINT can provide controlled flexibility in Docker container behavior.Best practices include using JSON array syntax, testing thoroughly, and documenting choices in the Dockerfile.Understanding the variances between CMD and ENTRYPOINT helps in creating effective Docker images and containers.Choosing between CMD and ENTRYPOINT depends on the need for adaptability or strict control in container operations.By mastering the usage of CMD and ENTRYPOINT, developers can ensure reliable and well-structured Docker images.