TLS, the successor of SSL, is used for encrypting traffic and authenticating connections like in HTTPS.While HTTPS starts TLS at the beginning, MySQL's TLS starts with negotation after client and server connection.Challenges with MySQL TLS include server certificates not being signed by known CAs and difficulty in obtaining certificates for internal hostnames.MySQL supports mutual-TLS authentication, but getting certificates from proper CAs can be complex.Default SSL mode in MySQL has security implications, with various levels of encryption and validation.MySQL's handshake process makes it challenging for proxies and load balancers to support TLS offloading.Long-lived connections in MySQL require re-authentication and handling of session-specific data upon connection interruptions.Oracle MySQL has made improvements in TLS integration, including default TLS usage, OpenSSL adoption, and simplified certificate setup.Overall, while MySQL has faced challenges with TLS implementation, efforts have been made to enhance security and ease of use.