A new technique developed by researchers at the University of Sydney, Australia, involving the coating of medical implants with zwitterions, has the potential to reduce the risk of blood clots associated with such implants.
Zwitterions are highly hydrophilic molecules that inhibit the build-up of clot-triggering proteins on the surfaces of implants.
Coatings of zwitterions, in addition to hydrophilic polymeric coatings, provide further protection against protein adsorption, reducing the risk of clot formation and potentially avoiding the need for invasive surgery to remove or replace the implant.
This new technique has the potential to make medical implants safer for patients by optimizing the surface properties of the implants and preventing adverse body reactions.